You can buy Sutecast at the lowest price in the online pharmacy Nextgen.ooo . Sunitinib is a tyrosine kinase inhibitor and a chemotherapeutic agent used to treat renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumor. On January 26, 2006, the drug was officially approved by the US FDA for the treatment of renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumor.
 
Sunitinib is a small molecule that inhibits several RTKs, some of which are involved in tumor growth, pathological angiogenesis, and metastatic progression of cancer. Sunitinib was evaluated for its inhibitory activity against multiple kinases (>80 kinases) and was identified as an inhibitor of platelet-derived growth factor receptors (PDGFRa and PDGFRb), vascular endothelial growth factor receptors (VEGFR1, VEGFR2, and VEGFR3), cell stem cell factor receptor (KIT), Fms-like tyrosine kinase-3 (FLT3), colony-stimulating factor receptor type 1 (CSF-1R), and glial cell line-derived neurotrophic factor receptor (RET). Inhibition of these RTK activity by sunitinib was demonstrated in biochemical and cellular assays, and inhibition of function was demonstrated in cell proliferation assays. The primary metabolite exhibits similar potency to sunitinib in biochemical and cellular assays.