You can buy Aivodx at the lowest price in the online pharmacy Nextgen.ooo . Ivosidenib is a first-in-class isocitrate dehydrogenase-1 (IDH1) inhibitor. IDH1 mutation and overexpression in some cancers lead to aberrant cell growth and proliferation. Ivosidenib inhibits mutated IDH1 by blocking enzymatic activity and further differentiation of cancer cells. Ivosidenib received accelerated approval from the FDA in July 2018 for the treatment of relapsed refractory acute myeloid leukemia in adults.
 
It is currently approved for the treatment of newly diagnosed acute myeloid leukemia in older adults in combination with azacitidine or as monotherapy, and locally advanced or metastatic cholangiocarcinoma in adults. The drug is only effective in patients with a predisposing IDH1 mutation.